![]() Its principal causes include pituitary adenoma (which can suppress production of adrenocorticotropic hormone (ACTH) and lead to adrenal deficiency unless the endogenous hormones are replaced) and Sheehan's syndrome, which is associated with impairment of only the pituitary gland. ![]() Secondary adrenal insufficiency: A condition which is caused by impairment of the pituitary gland or hypothalamus. Other subtypes include idiopathic (unknown) cause, congenital adrenal hyperplasia or an adenoma (tumor) of the adrenal gland. ![]() Other diseases that are more common in people with autoimmune adrenalitis include premature ovarian failure, celiac disease, and autoimmune gastritis with pernicious anemia. Hypogonadism may also present with this syndrome. Autoimmune adrenalitis may be part of Type 2 autoimmune polyglandular syndrome, which can include type 1 diabetes, hyperthyroidism, and autoimmune thyroid disease (also known as Hashimoto's thyroiditis), and Hashimoto's disease. The causes include:Īddison's disease or autoimmune adrenalitis: These are autoimmune conditions, constituting 80% of all cases. ![]() ![]() Hypoadrenalism or Adrenal Insufficiency (AI) can be classified as:Ī condition which is due to impairment of the adrenal glands. ![]()
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